Figure 10. HIV-1 Env-specific CD4+ (panel A) and CD8+ (panel B) T cell response.
Mice in groups of 6 were immunized with 105 PFU/ml of the indicated rNDV by the i.n. route on days 0 and 14. On day 56, splenocytes were isolated, stimulated with a pool of overlapping Env peptides, and processed for intracellular cytokine staining for IFN-γ and CD4 and CD8.