Table 2.
 Association between BMI and CVD mortality in east Asians
| Cause and No of CVD deaths | Body mass index at baseline | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| <15.0 | 15.0-17.4 | 17.5-19.9 | 20.0-22.4 | 22.5-24.9 | 25.0-27.4 | 27.5-29.9 | 30.0-32.4 | 32.5-34.9 | 35.0-50.0 | |
| All participants (n=820 439) | ||||||||||
| No of participants per BMI category | 2032 | 21 687 | 111 144 | 229 861 | 243 602 | 136 344 | 52 456 | 16 668 | 4210 | 2435 |
| CVD (n=38 738) | ||||||||||
| No of deaths per BMI category | 372 | 2375 | 7274 | 10 422 | 9711 | 5121 | 2160 | 841 | 245 | 217 |
| Hazard ratio (95% CI) | 2.16 (1.37 to 3.40) | 1.19 (1.02 to 1.39) | 1.06 (0.95 to 1.17) | 0.94 (0.89 to 0.98) | Reference | 1.09 (1.03 to 1.15) | 1.27 (1.20 to 1.35) | 1.59 (1.43 to 1.76) | 1.74 (1.47 to 2.06) | 1.97 (1.44 to 2.71) |
| CHD (n=9142) | ||||||||||
| No of deaths per BMI category | 58 | 401 | 1352 | 2324 | 2724 | 1358 | 562 | 252 | 72 | 39 |
| Hazard ratio (95% CI) | 1.7 (0.86 to 3.37) | 0.88 (0.71 to 1.10) | 0.85 (0.72 to 0.99) | 0.87 (0.79 to 0.95) | Reference |
1.14 (1.04 to 1.24) | 1.34 (1.19 to 1.52) | 1.93 (1.52 to 2.46) | 2.34 (1.70 to 3.22) | 1.88 (1.08 to 3.27) |
| Stroke (n=17 501) | ||||||||||
| No of deaths per BMI category | 138 | 922 | 3388 | 4747 | 4310 | 2365 | 1023 | 392 | 102 | 114 |
| Hazard ratio (95% CI) | 2.05 (0.75 to 5.61) | 1.12 (0.88 to 1.42) | 1.10 (0.96 to 1.27) | 0.92 (0.87 to 0.98) | Reference |
1.07 (0.98 to 1.16) | 1.24 (1.14 to 1.36) | 1.57 (1.38 to 1.79) | 1.51 (1.08 to 2.12) | 1.92 (1.43 to 2.57) |
| Ischaemic stroke (n=5771) | ||||||||||
| No of deaths per BMI category | 50 | 300 | 1062 | 1602 | 1368 | 841 | 330 | 140 | 41 | 37 |
| Hazard ratio (95% CI) | 1.51 (0.71 to 3.23) | 1.16 (0.89 to 1.5) | 1.05 (0.90 to 1.22) | 0.92 (0.84 to 1.01) | Reference |
1.21 (1.07 to 1.37) | 1.25 (1.02 to 1.52) | 2.00 (1.63 to 2.45) | 2.00 (1.33 to 3.01) | 1.71 (1.14 to 2.58) |
| Haemorrhagic stroke (n=6758) | ||||||||||
| No of deaths per BMI category | 41 | 337 | 1284 | 1871 | 1643 | 887 | 443 | 170 | 39 | 43 |
| Hazard ratio (95% CI) | 1.37 (0.91 to 2.07) | 1.05 (0.9 to 1.23) | 1.12 (0.91 to 1.38) | 0.99 (0.90 to 1.09) | Reference |
1.00 (0.90 to 1.11) | 1.28 (1.12 to 1.47) | 1.58 (1.27 to 1.95) | 2.08 (1.41 to 3.08) | 2.7 (1.44 to 5.05) |
Analyses for the calculation of hazard ratios were adjusted for baseline age, sex, cigarette smoking, alcohol consumption, educational attainment, marital status, urban residence, and baseline status of cancer. All analyses excluded first three years of follow-up.