Table 2. the distribution of alleles and genotypes of MMPs in related studies.
Allele | Genotype | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
case | control | case | control | HWE (p) | ||||||||
MMP1 -1607 1G/2G (rs1799750) | 1G | 2G | 1G | 2G | 1G1G | 1G2G | 2G2G | 1G1G | 1G2G | 2G2G | ||
Cai | 2010 | 34 | 126 | 56 | 124 | 6 | 22 | 52 | 15 | 26 | 49 | 0.002 |
Cheng | 2009 | 121 | 247 | 104 | 320 | 20 | 81 | 63 | 16 | 72 | 124 | 0.229 |
Diemen | 2011 | 182 | 174 | 1155 | 1079 | 44 | 94 | 40 | 295 | 565 | 257 | 0.669 |
Enewold | 2012 | 177 | 157 | 352 | 324 | 51 | 75 | 41 | 92 | 168 | 78 | 0.938 |
Haq | 2010 | 1006 | 948 | 911 | 841 | 273 | 460 | 244 | 228 | 455 | 193 | 0.231 |
Hersh | 2005 | 298 | 310 | 424 | 458 | 73 | 152 | 79 | 102 | 220 | 119 | 0.987 |
Korytina | 2008 | 271 | 365 | 261 | 377 | 65 | 141 | 112 | 51 | 159 | 109 | 0.580 |
Korytina | 2012 | 450 | 332 | 464 | 304 | 138 | 174 | 79 | 150 | 164 | 70 | 0.036 |
Lee | 2010 | 186 | 414 | 212 | 450 | 29 | 128 | 143 | 42 | 128 | 161 | 0.042 |
Tesfaigzi | 2006 | 121 | 123 | 259 | 255 | 32 | 57 | 33 | 70 | 119 | 68 | 0.236 |
Sun | 2005 | 32 | 86 | 40 | 178 | 5 | 22 | 32 | 9 | 22 | 78 | 0.001 |
Zhang | 2005 | 92 | 202 | 102 | 138 | 15 | 62 | 70 | 31 | 40 | 49 | <0.001 |
MMP3 -1171 5A/6A (rs35068180) | 5A | 6A | 5A | 6A | 5A5A | 5A6A | 6A6A | 5A5A | 5A6A | 6A6A | ||
Cheng | 2009 | 342 | 26 | 401 | 23 | 158 | 26 | 0 | 189 | 23 | 0 | 0.404 |
Korytina | 2012 | 22 | 780 | 46 | 664 | 0 | 22 | 369 | 0 | 46 | 309 | 0.192 |
Santus | 2009 | 140 | 154 | 131 | 135 | 25 | 90 | 32 | 36 | 59 | 38 | 0.194 |
Schirmer | 2009 | 89 | 93 | 88 | 110 | 26 | 37 | 28 | 23 | 42 | 34 | 0.161 |
Sun | 2012 | 84 | 76 | 67 | 81 | 26 | 32 | 22 | 19 | 26 | 29 | 0.072 |
MMP9 -1562 C/T (rs3918242) | C | T | C | T | CC | CT | TT | CC | CT | TT | ||
Cheng | 2009 | 233 | 135 | 320 | 104 | 76 | 81 | 27 | 124 | 72 | 16 | 0.229 |
Han | 2006 | 76 | 44 | 72 | 32 | 25 | 26 | 9 | 26 | 20 | 6 | 0.483 |
Hua | 2010 | 300 | 60 | 340 | 20 | 120 | 60 | 0 | 162 | 16 | 2 | 0.040 |
Ito | 2005 | 145 | 23 | 144 | 26 | 63 | 19 | 2 | 60 | 24 | 1 | 0.408 |
Korytina | 2008 | 560 | 76 | 556 | 82 | 248 | 64 | 6 | 241 | 74 | 4 | 0.523 |
Korytina | 2012 | 685 | 97 | 758 | 110 | 300 | 85 | 6 | 330 | 98 | 6 | 0.674 |
Lee | 2010 | 527 | 61 | 533 | 99 | 234 | 59 | 1 | 226 | 81 | 9 | 0.596 |
Minematsu | 2001 | 68 | 22 | 114 | 16 | 25 | 18 | 2 | 50 | 14 | 1 | 0.986 |
Schirmer | 2009 | 162 | 16 | 178 | 16 | 74 | 14 | 1 | 81 | 16 | 0 | 0.376 |
Tesfaigzi | 2006 | 195 | 43 | 439 | 67 | 82 | 31 | 6 | 192 | 55 | 6 | 0.392 |
Zhang | 2005 | 253 | 41 | 215 | 25 | 106 | 41 | 0 | 98 | 19 | 3 | 0.097 |
Zhou | 2004 | 194 | 2 | 186 | 14 | 96 | 2 | 0 | 86 | 14 | 0 | 0.452 |
MMP12 -82 A/G (rs2276109) | A | G | A | G | AA | AG | GG | AA | AG | GG | ||
Diemen | 2011 | 308 | 56 | 1905 | 345 | 130 | 48 | 4 | 812 | 281 | 32 | 0.202 |
Haq | 2010 | 1749 | 205 | 1524 | 228 | 782 | 185 | 10 | 657 | 210 | 9 | 0.082 |
Korytina | 2008 | 567 | 69 | 579 | 59 | 249 | 69 | 0 | 260 | 59 | 0 | 0.069 |
Korytina | 2012 | 700 | 82 | 787 | 85 | 309 | 82 | 0 | 353 | 81 | 2 | 0.243 |
Schirmer | 2009 | 194 | 28 | 186 | 16 | 84 | 26 | 1 | 85 | 16 | 0 | 0.387 |
Zhang | 2004 | 289 | 7 | 386 | 8 | 141 | 7 | 0 | 189 | 8 | 0 | 0.877 |