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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Nat Neurosci. 2013 Aug 4;16(9):1291–1298. doi: 10.1038/nn.3480

Figure 7. LM-4131 does not exert overt cannabimimetic effects in vivo.

Figure 7

(a) Effects of vehicle, LM-4131, and Win 55212-2 on rectal temperature over time. (b) Effects of vehicle, LM-4131, and Win 55212-2 on catalepsy over time. (c) Effects of vehicle, LM-4131, and Win 55212-2 on antinociception in the hot plate test. (d) Effects of LM-4131 on novel object recognition. F and P values for drug treatment effects by two-way ANOVA shown for (a-b), and for novelty recognition factor by two-way ANOVA in (d); F and P values for drug effect by one-way ANOVA shown for (c). Multiplicity corrected P values by Sidak's multiple comparisons post hoc test (a-b, and d) and by Dunnett's post hoc test (c) are shown. n =number of mice per treatment group indicated in figure. Error bars represent S.E.M.