Table 1.
Identified long-lived proteins. Listed are the names (column 1), average 15N fractional abundance at 6-months post-chase (column 2), number of peptides used to determine 15N fractional abundance (column 3), subcellular localization as plotted in Figure 1C (column 4), and cellular process as plotted in Figure 1C (column 5).
| Protein | % | Peptides | Localization | Process |
|---|---|---|---|---|
| Histone H1.0 | 5.36 | 6 | Nucleus | Histones |
| Histone H1.1 | 7.87 | 3 | Nucleus | Histones |
| Histone H1.2 isol | 10.64 | 2 | Nucleus | Histones |
| Histone H1.2 iso2 | 2.13 | 1 | Nucleus | Histones |
| Histone H1.2 iso3 | 62.50 | 1 | Nucleus | Histones |
| Histone H1.5 | 35.23 | 15 | Nucleus | Histones |
| H2A | 15.63 | 10 | Nucleus | Histones |
| Macro H2A | 9.10 | 3 | Nucleus | Histones |
| H2A.x | 17.42 | 6 | Nucleus | Histones |
| Histone H2B | 21.70 | 19 | Nucleus | Histones |
| Histone H3.1 | 90.39 | 3 | Nucleus | Histones |
| Histone H4 | 29.54 | 22 | Nucleus | Histones |
| Nup205 | 47.18 | 14 | Nucleus | NPC |
| Nup155 | 39.43 | 10 | Nucleus | NPC |
| Nup93 | 50.25 | 9 | Nucleus | NPC |
| Nup107 | 13.82 | 5 | Nucleus | NPC |
| Nup160 | 20.12 | 8 | Nucleus | NPC |
| Nup96 | 19.48 | 9 | Nucleus | NPC |
| Nup188 | 8.33 | 2 | Nucleus | NPC |
| Nup85 | 12.24 | 6 | Nucleus | NPC |
| MBP | 20.28 | 30 | PM/ECM | Myelin Sheath |
| PLP | 18.53 | 11 | PM/ECM | Myelin Sheath |
| MOG | 14.33 | 4 | PM/ECM | Myelin Sheath |
| Nef3 | 5.91 | 7 | PM/ECM | Myelin Sheath |
| Cnp1 | 4.82 | 13 | PM/ECM | Myelin/Enzyme |
| Enpp6 | 34.39 | 6 | PM/ECM | Enzyme |
| Sirt2 | 11.49 | 6 | Cyto/Nucleus | Enzyme |
| Asrgl1 | 78.70 | 2 | Cyto | Enzyme |
| igsf8 | 11.99 | 4 | PM/ECM | other |
| Lamin-B1 | 13.18 | 32 | Nucleus | Structural |
| Lamin-B2 | 6.63 | 9 | Nucleus | Structural |
| Cspg2 | 17.21 | 4 | PM/ECM | Structural |
| Lamc1 | 10.62 | 19 | ECM | Structural |
| Col6a1 | 35.61 | 9 | ECM | Structural |
| Col6a3 | 36.72 | 9 | ECM | Structural |
| Col4a2 | 18.51 | 3 | ECM | Structural |
| Col1a1 | 9.10 | 4 | ECM | Structural |