Table A1.
Effect of CD8 activation (% CD38+/HLA-DR+) and naïve CD4 percentage (% CD45RA+/CD62L+) on the slope of change in CD4 outcome in virally suppressed subjects
| Predictor | Effect on mean CD4 count per year (95% CI)
|
|
|---|---|---|
| Separate univariate models | Model with both CD8 activation and naïve CD4 percentage | |
| CD8 activationa (per 5 percentage points higher) | −3 (−5, −1) | −3 (−5, −1) |
| Naïve CD4 %a (per 5 percentage points higher) | 3 (1, 4) | 2 (1, −4) |
a
Each subject’s average level, measured primarily during years 3–5, was used as the predictor.