Figure 4. Aspergillus-induced inflammatory cytokines are increased in TLR4 deficient mice following 2nd and 3rd patch.
(A) TSLP, (B) IL17C, (C) S100A8 and S100A9, (D) IL1β, (E) IL6, (F) TNFα, and (G) CXCL2 mRNA skin levels were assessed by quantitative real-time PCR after the 2nd and 3rd patch (n=5–8 and n=6–12 respectively) and expressed as a ratio over the house keeping gene HPRT (*p< 0.05 **p< 0.01 one way ANOVA with Bonferroni’s Multiple Comparison Test; n.s. not significant).
