Figure 1.
Chemical structures. (A) Structures of polyamides 1–4. The compounds only vary by the amino substitution on the γ-turn unit. (B) The preferred DNA binding sequence of the polyamide core. Polyamide 1 is shown bound to the sequence 5′-WGWWCW-3′. Closed circles represent imidazole units and open circles represent pyrrole units.