Table 1.
Simple (Monthly) Assessment |
Findings | Possible Interventions |
---|---|---|
BW Serum albumin |
Continuous decline or <85% IBW <4.0 g/dL |
Suspect uremic malnutrition and perform more detailed nutritional assessment |
Serum creatinine | Relatively low predialysis values |
No intervention needed at this point |
Detailed Assessment | Possible Interventions (simple) | |
Serum prealbumin | <30 mg/dL, and/or | Dietary counseling: DPI ≥ 1.2 g/kg/d, energy intake 30–35 kcal/d |
Serum transferrin | <200 mg/dL, and/or | |
IGF-1 | <200 ng/mL, and/or | CHD and peritoneal dialysis |
LBM and/or fat mass | Unexpected decrease | Increase dialysis dose to Kt/V > 1.4 |
SGA | Worsening | Use biocompatible membranes |
Upper gastrointestinal motility enhancer |
||
CKD | ||
Consider timely initiation of CDT | ||
Repeat Detailed Assessment (2–3 months from previous) |
Possible Interventions (moderate to complex) |
|
Serum prealbumin | <30 mg/dL, and/or | Nutritional supplements: |
Serum transferrin | <200 mg/dL, and/or | Oral, enteric tube feeding, IDPN (requires Medicare approval) |
IGF-I | <200 ng/mL, and/or | |
Serum creatinine | Relatively low predialysis values, and/or |
Anabolic factors (experimental): rhGH, rhIGF-I |
LBM and/or fat mass | ||
C-reactive protein< | unexpected decrease >10 mg/L |
Appetite stimulants (experimental) |
Anti-inflammatory (experimental) |
Adapted with permission from Pupim et al.38
Abbreviations: BW, body weight; IBW, ideal body weight; IGF-1, insulin-like growth factor-1; LBM, lean body mass; SGA, subjective global assessment; DPI, dietary protein intake; CDT, chronic dialysis treatment.