Fig. 2.

Energy balance in Mrap2^−/− mice. (A) Cumulative food intake (upper panels) and weight (lower panels) in ad libitum fed Mrap^+/+ vs. Mrap2^−/− males (n=10 vs. 11) and females (n=11 vs. 8). (B) Energy expenditure in ad libitum-fed Mrap^+/+ vs. Mrap2^−/− mice. Upper panels, continuous measurement over 3 days, males (n=3 vs. 4), females (n=4 vs. 3), ages 30–34 days. Lower panels: body weight vs. energy expenditure, integrated over 24 h, males (n=18 vs. 14, ages 30–45 days), females (n=16 vs. 11, ages 30–42 days). Analysis by ANCOVA showed no differences between genotypes (males, p=.38, females, p=.67).