Table 2.

Categories of EPS-related adverse events: MedDRA preferred terms

EPS-related AE subgroups	MedDRA preferred terms
Tremor	Tremor, essential tremor, intention tremor
Dystonia	Oculogyration, oculogyric crisis, trismus, tongue spasm, tongue paralysis, cervical spasm, emprosthotonus, myotonia, pleurothotonus, risus sardonicus, muscle spasms, blepharospasm, dystonia, opisthotonus, torticollis, facial spasm, muscle contracture
Hyperkinesia	Akathisia, hyperkinesia, periodic limb movement disorder, restless legs syndrome, restlessness
Parkinsonism	Hypertonia, bradykinesia, cogwheel rigidity, drooling, musculoskeletal stiffness, akinesia, hypokinesia, nuchal rigidity, Parkinsonian gait, Parkinsonian rest tremor, parkinsonism, muscle rigidity, muscle tightness, glabellar reflex abnormal, on and off phenomenon, Parkinson’s disease, Parkinsonian crisis, extrapyramidal disorder, masked facies
Dyskinesia	Dyskinesia, muscle contractions involuntary, movement disorder, muscle twitching, athetosis, chorea, choreoathetosis, tardive dyskinesia, myoclonus

Abbreviations: AE, adverse event; EPS, extrapyramidal symptoms; MedDRA, Medical Dictionary for Regulatory Activities.