Time (days) | −7 | 1 | 8 | 15 | 22 | 29 | 36 | 43 | 64 | 92 |
---|---|---|---|---|---|---|---|---|---|---|
LAI PBO | 0.1 (0.3) | 0.1 (0.25) | 0.1 (0.22) | 0.1 (0.25) | – | – | 0.1 (0.23) | 0.1 (0.2) | 0.3 (0.7) | 0.4 (1.04) |
LAI 25 mg | 0.1 (0.28) | 0.1 (0.25) | 0.1 (0.2) | – | – | – | – | – | – | 0.3 (1.05) |
LAI 50 mg | 0.2 (0.3) | 0.2 (0.28) | 0.1 (0.26) | 0.2 (0.35) | – | – | 0.1 (0.26) | 0.1 (0.24) | 0.4 (0.92) | 0.3 (0.98) |
LAI 100 mg | 0.1 (0.26) | 0.1 (0.25) | 0.1 (0.21) | 0.2 (0.32) | – | – | 0.1 (0.21) | 0.1 (0.22) | 0.4 (0.89) | 0.3 (0.9) |
LAI 150 mg | 0.1 (0.23) | 0.1 (0.21) | 0.1 (0.19) | – | – | – | – | – | – | 0.3 (1.11) |
Oral PBO | – | 0.1 (0.26) | 0.1 (0.26) | 0.1 (0.26) | 0.1 (0.24) | 0.1 (0.22) | 0.1 (0.2) | 0.1 (0.21) | – | – |
Oral 3 mg | – | 0.2 (0.34) | 0.1 (0.3) | 0.2 (0.35) | 0.2 (0.36) | 0.1 (0.28) | 0.1 (0.23) | 0.1 (0.24) | – | – |
Oral 6 mg | – | 0.1 (0.18) | 0.1 (0.19) | 0.1 (0.16) | 0.1 (0.18) | 0.1 (0.14) | 0.1 (0.15) | 0.1 (0.11) | – | – |
Oral 9 mg | – | 0.1 (0.21) | 0.2 (0.28) | 0.2 (0.27) | 0.2 (0.28) | 0.2 (0.3) | 0.2 (0.26) | 0.1 (0.24) | – | – |
Oral 12 mg | – | 0.1 (0.23) | 0.1 (0.27) | 0.1 (0.25) | 0.1 (0.26) | 0.1 (0.28) | 0.1 (0.25) | 0.1 (0.19) | – | – |
Oral 15 mg | – | 0.2 (0.33) | 0.2 (0.29) | 0.2 (0.35) | 0.2 (0.37) | 0.2 (0.29) | 0.2 (0.31) | 0.1 (0.29) | – | – |
Oral OLZ | – | 0.1 (0.27) | 0.1 (0.24) | 0.1 (0.2) | 0.1 (0.2) | 0.1 (0.21) | 0.1 (0.18) | 0.1 (0.18) | – | – |
Abbreviations: LAI, long-acting injectable; OLZ, olanzapine; PBO, placebo.