Figure 1. PDGF-B; Ink4a-ARF deficient and PDGF-B; p53 deficient BSG models overexpress all three D-type cyclins.
Western blot for cyclins D1, D2, D3, CDK 4 and CDK 6. From left to right: lane 1 is normal brainstem from Ntv-a; p53 floxed mice, lanes 2 and 3 are two PDGF-B; p53 deficient BSGs, lane 4 is normal brainstem from Ntv-a; Ink4a-ARF deficient mice, lanes 5 and 6 are two PDGF-B; Ink4-ARF deficient BSGs.