Table 1. Serum biological examinations in each group of rats.
Group | n | ALT (U/L) | AST (U/L) | TC (mmol/L) | TG (mmol/L) |
---|---|---|---|---|---|
Control | 12 | 45.30±11.35 | 71.80±9.46 | 1.81±0.20 | 0.41±0.10 |
8th week | 6 | 65.00±10.39#* | 93.17±14.27#* | 2.77±0.31#* | 0.69±0.12#* |
12th week | 6 | 105.50±13.74#* | 128.67±14.92#* | 3.45±0.32#* | 0.86±0.10#* |
16th week | 6 | 120.50±11.06#* | 149.50±9.20#* | 3.85±0.19#* | 1.02±0.13#* |
20th week | 6 | 138.67±9.63#* | 178.00±8.07#* | 4.15±0.23#* | 1.24±0.18#* |
24th week | 6 | 163.00±17.34# | 193.00±8.85# | 4.51±0.21# | 1.41±0.08# |
Simvastatin | 6 | 132.67±7.09#* | 152.50±13.32#* | 4.20±0.23#* | 1.25±0.10#* |
F value | 92.92 | 110.89 | 62.70 | 36.27 | |
P value | <0.01 | <0.01 | <0.01 | <0.01 |
# P<0.05, compared with the control group; *P<0.05, compared with 24th week group