Table 2. Association between position 400 (alanine vs threonine) and polymerase domain mutations in subtype B viruses from patients failing therapy.

Mutated position	p-value*	A400 (%)	T400 (%)
M184	0.0004	30	65
T215	0.0036	28	57
L74	0.0037	5	27
V118	0.0045	10	34
K70	0.0063	3	22
D67	0.0086	18	42
K103	0.0112	3	19
K219	0.0229	18	39
M41	0.0310	25	46
Y181	0.0357	3	17
G190	0.0357	3	17

^*p-values <0.05 are considered significant.