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. 2013 Oct 2;8(10):e74130. doi: 10.1371/journal.pone.0074130

Figure 4. Antioxidant NAC ameliorates TLR2−/−-aggravated HCC progression.

Figure 4

(A) Representative images of gross liver specimens from TLR2−/− mice treated with or without NAC at six months post-DEN injection. Scale bars, 1 cm. (B) NAC treatment decreased the number of surface tumor nodules in TLR2−/− mice. Each dot represents the tumor nodules from each mouse. Scale bars indicate the mean ± SD (n = 20 per group). (C) NAC treatment decreased the volume of surface tumors. Data are presented as mean ± SD (n = 20 per group). (D) Representative H&E stained liver sections from TLR2−/− mice treated with or without NAC. Scale bar, 500 µm. (E) The calculated tumor area (percentage of liver) is presented as mean ± SD (n = 20 per group).