Figure 4. Tissue pharmacokinetics of GNRs after I.V. and I.T. administration to EACC tumor bearing mice.

GNRs were administered by I.V. (◌) or I.T. (●) injection (1.5 mg/kg) to tumor bearing mice. Tissue concentration of gold in tumor (A), liver (B), spleen (C), and kidney (D) tissues were assayed for Gold conetnt at different time intervals until two weeks. Data are presented as mean ± SEM (n=3).