Table II.

Correlation between the expression of microRNAs and clinicapathological characteristics in serum samples from patients with ccRCC.

		miR-34a		miR-224		miR-141		miR-21
Characteristic	n	2−ΔΔCt ± SD	P-value	2−ΔΔCt ± SD	P-value	2−ΔΔCt ± SD	P-value	2−ΔΔCt ± SD	P-value
Gender
Male	8	24.7±22.3	0.212a	161.4±104.9	0.011b	0.1E-5±0.2E-5	0.606b	38.8±60.0	0.860a
Female	4	9.2±5.7		15.4±16.3		0.1E-6±0.7E-7		32.8±31.8
Age (years)
≤50	5	21.1±27.0	0.827a	27.2±29.9	0.056a	0.1E-6±0.6E-7	0.533b	29.7±28.4	0.703a
>50	7	18.4±14.6		173.8±147.7		0.1E-5±0.2E-5		41.9±64.2
Clinical stage
I	9	20.6±22.7	0.758a	69.6±79.9	0.229a	0.1E-5±0.2E-5	0.480a	13.7±16.7	0.013b
II+III	3	16.3±5.3		242.2±198.1		0.1E-6±0.1E-7		106.1±58.8
Pathological grade
I	3	41.4±29.9	0.116b	57.1±48.1	0.782b	0.1E-6±0.1E-7	1.000b	23.7±27.6	0.629a
II+III+IV	9	12.2±8.1		131.3±149.8		0.1E-5±0.2E-5		41.2±57.2
Tumor size (cm)
≤7	9	21.5±21.7	0.566a	100.1±129.5	0.596a	0.4E-6±0.9E-6	0.770b	28.5±29.7	0.926b
>7	3	13.5±12.6		150.5±168.5		0.2E-5±0.4E-5		61.6±97.1
Renal capsule invasion
No	2	3.3±3.2	0.216a	40.6±2.6	0.667b	0.1E-6±0.0	0.644a	10.1±12.8	0.441a
Yes	10	22.7±19.9		127.2±143.0		0.1E-5±0.2E-5		42.1±54.2

^aANOVA;

^bKruskal-Wallis test.

ccRCC, clear cell renal cell carcinoma.