Table 3.

Multivariable Cox Proportional Hazards Model Predicting Incident Coronary Artery Disease in GeneSTAR (n=1483)^*

Characteristic	Hazard Ratio (95% CI)	P
Baseline age (years) †	1.38 (1.18–1.61)	<0.0001
Male sex	2.87 (2.03–4.06)	<0.0001
African American race	0.51 (0.35–0.74)	0.0004
Hypertension	1.65 (1.19–2.30)	0.003
LDL cholesterol (mg/dl) †	1.31 (1.15–1.49)	<0.0001
HDL cholesterol (mg/dl) †	0.85 (0.70–1.04)	0.11
Diabetes mellitus	1.99 (1.25–3.16)	0.0036
Current smoker	1.36 (0.99–1.87)	0.06
General Well-Being (total score) †	0.67 (0.58–0.79)	<0.0001

^*Adjusted for education, being married, BMI, physical fitness, and having a psychiatric diagnosis and/or being on psychiatric medications, all non-significant (p>0.2)

^†Continuous variables were standardized by dividing by their standard deviation: age SD=7.19; LDL SD=41.3; HDL SD=16.9; GWBS SD=16.9.

BMI=body mass index

CI=confidence interval

GWBS=General Well-Being Schedule

HDL=high density lipoprotein

LDL=low density lipoprotein

SD=standard deviation