Table V.
Correlation between rs7105934 genotypes or AJCC stage and cyclin D1 expression in ccRCC specimens.
| Cyclin D1 expression
|
P-value | rsa | |||
|---|---|---|---|---|---|
| − | + | ++/+++ | |||
| rs7105934 | |||||
| GG | 24 | 25 | 27 | 0.844 | 0.021 |
| GA | 5 | 3 | 5 | ||
| AA | 0 | 0 | 1 | ||
| GG | 24 | 25 | 27 | 0.884 | 0.016 |
| GA + AA | 5 | 3 | 6 | ||
| AJCC (2002) stage | |||||
| I | 16 | 15 | 26 | 0.046 | −0.211 |
| II | 3 | 3 | 2 | ||
| III | 10 | 10 | 5 | ||
a
Spearman’s correlation coefficient. AJCC, American Joint Committee on Cancer; −, negative (<5% positive cancer cells); +, weak (5–20% positive); ++, moderate (20–60% positive); +++, strong (>60% positive); ccRCC, clear cell renal cell carcinoma.