Figure 2.

TMPZ induces apoptosis in SGC7901 gastric cancer cells. The cells were treated with different doses of TMPZ for 24 h and then stained with fluorescence-conjugated Annexin V and PI, and analyzed by flow cytometry. (A) Representative flow cytometric dot plots (x-axis, annexin V staining; y-axis, PI staining). (B) Quantitation of apoptotic cell population as shown in (A). The data are presented as the mean ± SD of three independent experiments. ^**P<0.01 compared with the control cells. TMPZ, tetramethylpyrazine; PI, propidium iodide.