Table II.

Correlation between IMP3 protein and clinicopathological factors in CRA.

		IMP3 expression, n
Parameters	Cases, n	−	+/++	χ2	P-value
Age (years)				1.073	0.302
>59	82	16	66
≤59	104	27	77
Gender				0.034	0.854
Male	119	27	92
Female	67	16	51
Histological grade				3.176	0.076
Well-differentiated	99	28	71
Moderately/poorly-differentiated	87	15	72
Tumor size (cm)				1.494	0.223
≤5	115	30	85
>5	71	13	58
Lymphoid metastasis				9.430	0.002
Present	75	26	49
Absent	111	17	94
Clinical stage				10.713	0.001
I–II	65	24	41
III–IV	121	19	102
CEA				1.473	0.226
Normal	76	21	55
Increased	110	22	88

IMP3, insulin-like growth factor-II mRNA-binding protein 3; CRA, colorectal adenocarcinoma; CEA, carcinoembryonic antigen level; −, no IMP3 staining; +/++, weak/strong IMP3 staining.