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Effect of fucoxanthin on cyp1a1 gene expression. (A) The cells were treated with 16.5 μM fucoxanthin for the indicated time. (B) The cells were treated with fucoxanthin (9.0, 16.5 and 27.0 μM) for 24 h. The expression of cyp1a1 was normalized to that of 36b4. (C) Representative data for cyp1a1 expression as determined by northern blot analysis. Cyp, cytochrome P450; Fx, Fucoxanthin. Data are expressed as the mean ± SD (n=3). *P<0.05 and **P<0.01 vs. the control.
