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Inhibition of human recombinant CYP enzyme activity by fucoxanthin. (A) CYP1A1 activity was determined using the P450-Glo assay and microsomes containing recombinant human CYP1A1. (B) CYP1A2 and (C) CYP3A4 activity was determined using Vivid CYP450 Screening kits supplied with baculosomes containing each CYP. Data are expressed as the mean ± SD (n=2–4). CYP, cytochrome P450.
