Table 1. Demographic details of SMC brain series.
Whole series (n=104) |
Controls (n=35) |
Schizophrenia (n=35) |
Bipolar disorder (n=34) |
|
---|---|---|---|---|
Sex (M:F) | 68:36 | 26:9 | 26:9 | 16:18 |
Age (years) | 44.0±9.0 | 44.2±7.6 | 42.6±8.5 | 45.4±10.7 |
Fresh brain weight (g) | 1427±134 | 1444±148 | 1442±107 | 1395±142 |
Side of brain studied (L:R) | 52:52 | 16:19 | 17:18 | 19:15 |
Brain pH | 6.50±0.28 | 6.61±0.27 | 6.47±0.24 | 6.43±0.30 |
RIN for cerebellar mRNA | 6.26±1.73 | 6.15±2.02 | 6.43±1.45 | 6.21±1.72 |
RIN for hippocampal mRNA | 4.80±1.27 | 5.03±1.13 | 4.68±1.36 | 4.68±1.33 |
RIN for cingulate mRNA | 4.81±1.42 | 4.72±1.56 | 5.07±1.52 | 4.89±1.82 |
Autopsy delay (hours) | 32.8±16.1 | 29.4±12.9 | 31.4±15.5 | 37.9±18.6 |
Storage time (months) | 86.6±23.2 | 81±18 | 87±23 | 93±26 |
Values are mean±S.D.
RIN: RNA integrity number; higher numbers indicate more intact RNA.