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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: Biochem J. 2009 May 1;419(3):645–653. doi: 10.1042/BJ20082368

Figure 1. LE synergizes with insulin to induce Gck expression in rat liver hepatocytes.

Figure 1

(A) The synergistic effect at 1 nM insulin (mean ± S.D., n = 7 with four batches of LE preparation, all *P < 0.001). (B) The synergistic effect of LE at increasing concentrations of insulin (means ± S.D., n = 3, all *P < 0.02 for comparing the control group with the LE group at the corresponding insulin concentration). Hepatocytes were treated with indicated concentrations of insulin in the absence or presence of LE for 6 h. The Gck mRNA expression level in the vehicle control group was arbitrarily assigned a value of 1.