Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 3;7:133. doi: 10.3389/fncom.2013.00133

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Avery, Dutt and Krichmar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The MOT filters out noise to improve behavioral performance. This figure shows the firing rates of all MOT neurons for a single trial. During low DA (A–C), optimal DA + high NE (F) and optimal NE + high DA (H) conditions, working memory in the PFC is extremely noisy and it is difficult to differentiate which of the columns would correctly drive the motor response (D,E,G,I do not show significant noise). As can be seen in this figure, however, some of this noise is filtered out in the MOT with lateral inhibition. Lateral inhibition allows the initially strong response from the preferred direction (blue, in these cases) to dominate and win out over other directions. This suggests that lateral inhibition may be a means for the MOT to improve behavioral performance even noise in the PFC is high. Firing rates were smoothed using a simple moving average.