Table 4.
Neuromodulatory factor (μ) effects for differing neuromodulatory concentrations.
| Low DA + low NE | Low DA + optimal NE | Low DA + high NE | |||||||
|---|---|---|---|---|---|---|---|---|---|
| AMPA | NMDA | I | AMPA | NMDA | I | AMPA | NMDA | I | |
| L3 exc(pref) → L3 exc(pref) | 0.1 | 10 | – | 0.1 | 15 | – | 0.1 | 15 | – |
| L3 exc(npref) → L3 exc(pref) | 1.4 | 1.4 | – | 1.4 | 1.4 | – | 1.4 | 1.4 | – |
| L3 exc | – | – | – | – | – | – | – | – | 0.8 |
| Optimal DA + low NE | Optimal DA + optimal NE | Optimal DA + high NE | |||||||
| AMPA | NMDA | I | AMPA | NMDA | I | AMPA | NMDA | I | |
| L3 exc(pref) → L3 exc(pref) | 0.1 | 10 | – | 0.1 | 15 | – | 0.1 | 15 | – |
| L3 exc(npref) → L3 exc(pref) | 1 | 1 | – | 1 | 1 | – | 1 | 1 | – |
| L3 exc | – | – | – | – | – | – | – | – | 0.8 |
| High DA + low NE | High DA + optimal NE | High DA + high NE | |||||||
| AMPA | NMDA | I | AMPA | NMDA | I | AMPA | NMDA | I | |
| L3 exc(pref) → L3 exc(pref) | 0.1 | 10 | – | 0.1 | 15 | – | 0.1 | 15 | – |
| L3 exc(pref) → L3 exc(npref) | 1 | 1 | – | 1 | 1 | – | 1 | 1 | – |
| L3 exc | – | – | 0.8 | – | – | 0.8 | – | – | 0.67 |