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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: J Nucl Med. 2011 Feb 14;52(3):369–378. doi: 10.2967/jnumed.110.082404

Table 3.

Sensitivity and specificity (along with the corresponding 95% CI) of three SUV based measurements, two co-occurrence features and two size-zone features. On the top: evaluation of parameters to distinguish PR or CR, on the bottom: evaluation of parameters to differentiate complete responders

Parameters Sensitivity (%) 95% CI (%) Specificity (%) 95% CI (%)
NR vs. PR+CR SUVmax 53 [35.1–70.2] 73 [39.0–94.0]
SUVmean 71 [52.5–84.9] 45 [16.7–76.6]
SUVpeak 56 [37.9–72.8] 73 [39.0–94.0]
Local Homogeneity 88 [71.8–96.6] 73 [39.0–94.0]
Local Entropy 79 [61.1–91.0] 82 [48.2–97.7]
Size-zone variability 76 [58.8–89.8] 91 [58.7–99.8]
Intensity variability 76 [58.7–89.3] 91 [58.7–99.8]

NR+PR vs. CR SUVmax 46 [19.2–74.9] 91 [75.0–98.0]
SUVmean 62 [31.6–86.1] 81 [63.6–92.8]
SUVpeak 62 [31.6–86.1] 81 [63.6–92.8]
Local Homogeneity 92 [61.5–99.8] 56 [37.7–73.6]
Local Entropy 92 [61.5–99.8] 69 [50.0–83.9]
Size-zone variability 92 [64.0–99.8] 69 [50.0–83.9]
Intensity variability 85 [54.6–98.1] 75 [56.6–88.5]