Table 2.
Characteristics of studies that included AKI patients treated with either peritoneal dialysis or extracorporeal blood purification
| Reference | Study Type(Country) | Study Period | Mean Age (yr) | ICU Patients (%) | Sepsis (%) | EBP Used | Mean APACHE II Score | Predominant Causes of AKI (Stated in the Studies) | PD | EBP | Total on RRT | Overall Mortality (%) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Mortality | N | Mortality | |||||||||||
| Watcharotone (29) | Retr.(Thailand) | January 2005 to December 2009 | 61.6 | 69.7 | 84.8 | Int. HD | 23.1 | Not stated | 62 | 47 (75.8%) | 83 | 52 (62.7%) | 145 | 68.3 |
| George (37) | RCT(India) | June 2005 to June 2008 | 46.9 | 100.0 | 38.0 | CVVHDF | 18.1 | Sepsis (38.0%), prerenal (34.0%), leptospirosis (10.0%), snake bite (6.0%) | 25 | 18 (72.0%) | 25 | 21 (84.0%) | 50 | 78.0 |
| Gabriel (10) | RCT(Brazil) | January 2004 to December 2006 | 63.4 | 77.4 | 44.5 | Daily HD | 25.1 | Sepsis (44.5%), prerenal (39.2%), postsurgery (22.5%) | 60 | 35 (58.0%) | 60 | 32 (53.0%) | 120 | 55.5 |
| Chow A (36) | Pros.(Malaysia) | March 1994 to June 1994 | 57.7 | 29.5 | 41.0 | Int. HD, CVVHDF | NA | Prerenal (43.6%), sepsis (41.0%), toxins (10.3%) | 9 | 6 (66.7%) | 3 | 2 (66.7%) | 12 | 66.7 |
| Chow B (36) | Pros.(Malaysia) | November 2004 to February 2005 | 55.6 | 13.3 | 37.9 | Int. HD, CVVHDF | NA | Prerenal (53.5%), sepsis (37.9%), toxins (6.2%) | 26 | 12 (46.2%) | 4 | 3 (75.0%) | 30 | 46.7 |
| Mahajan (35) | Retr.(India) | April 2000 to March 2004 | 66.4 | NA | 21.6 | Int. HD | NA | Prerenal (33.0%), sepsis (21.6%), toxins (16.1%) | 95 | 46 (48.4%) | 37 | 25 (67.6%) | 132 | 53.8 |
| Arogundade (34) | RCT(Nigeria) | December 1998 to February 2001 | 44.0 | NA | 17.5 | Int. HD | NA | Sepsis (87.5%), obstruction (12.5%) | 4 | 0 (0.0%) | 4 | 0 (0.0%) | 8 | 0.0 |
| Phu (33) | RCT(Vietnam) | 1993–1998 | 35.5 | 100.0 | 31.4 | CVVHDF | NA | Malaria (68.6%), sepsis (31.4%) | 36 | 17 (47.0%) | 34 | 5 (15.0%) | 70 | 31.5 |
| Bellomo (15) | Retr.(Australia) | 1983–1993 | 58.3 | 100.0 | 66.6 | HDF, Int. HD | 27.3 | Sepsis (66.0%) | 16 | 12 (75.0%) | 218 | 139 (63.8%) | 234 | 64.5 |
| Kumar (32) | Retr.(India) | July 1987 to March 1988 | 46.3 | NA | NA | Int. HD | NA | Diarrheal illness (100%) | 42 | 25 (59.5%) | 3 | 2 (66.7%) | 45 | 60.0 |
| Hadidy (31) | Retr.(Serbia) | 1980–1986 | 38.0 | NA | NA | Int. HD | NA | Obstruction, surgery, trauma (64.0% of men); pregnancy, GN (56.0% of women) | 4 | 0 (0.0%) | 77 | 26 (33.8%) | 81 | 30.9 |
| Werb (30) | Retr.(Canada) | July 1974 to June 1976 | NA | 100.0 | 28.0 | Int. HD | NA | Sepsis (28.0%), prerenal (17.0%) | 13 | 9 (69.2%) | 19 | 12 (65.0%) | 32 | 65.5 |
ICU, intensive care unit; EBP, extracorporeal blood purification; APACHE II, Acute Physiology, Age, Chronic Health Evaluation II; PD, peritoneal dialysis; RRT, renal replacement therapy; Retr., retrospective; Int., intermittent; HD, hemodialysis; RCT, randomized control trial; CVVHDF, continuous venovenous hemodiafiltration; Pros., prospective; NA, results not available; HDF, hemodiafiltration.