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. Author manuscript; available in PMC: 2014 Jul 23.
Published in final edited form as: ACS Nano. 2013 Jun 14;7(7):5724–5731. doi: 10.1021/nn402517v

Figure 3.

Figure 3

Switchable aptamer micelle flares respond to target ATP molecules in vitro. (a) Fluorescence titration of SAMF (1 μM) against increased concentrations of ATP (0.1-3.0 mM). (b) Time course of fluorescence associated with the binding of target molecules. The concentration of ATP was 1 mM. (c) Switchable aptamer micelle flares distinguish ATP from its analogs: TTP, GTP, CTP and UTP. The concentration of ATP and its analogs were 2 mM. (d) Cytotoxicity assay of HeLa cells treated with different concentrations of SAMFs (0, 0.2, 0.5, 1, 2 μM).