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. Author manuscript; available in PMC: 2014 Feb 23.

Published in final edited form as: J Pharm Biomed Anal. 2012 Nov 15;74:291–297. doi: 10.1016/j.jpba.2012.10.033

Fig. 5 — Experiment E. Ten-minute time course of heroin degradation after spiking of 100 ng/mL heroin into rat brain homogenate (brain homogenized with formate containing NaF ( ) or without NaF ( , run in duplicate) and brain homogenized with water containing NaF ( ), or without NaF ( ). For samples homogenized with formate buffer and no NaF, corresponding 6-MAM levels are observed ( , run in duplicate). Samples were stored on ice during experiment.

Inline graphic — Experiment E. Ten-minute time course of heroin degradation after spiking of 100 ng/mL heroin into rat brain homogenate (brain homogenized with formate containing NaF ( ) or without NaF ( , run in duplicate) and brain homogenized with water containing NaF ( ), or without NaF ( ). For samples homogenized with formate buffer and no NaF, corresponding 6-MAM levels are observed ( , run in duplicate). Samples were stored on ice during experiment.