(c)
| Multiple logistic regression model for urinary tract cancerc | |||
|---|---|---|---|
| Study Chinese herb | No. of cases/controls | Adjusted OR | 95% CI |
| Mu-Tong | |||
| 0 g | 3,987/149,464 | 1.0 | |
| 1–60 g | 489/22,354 | 1.0 | 0.9–1.2 |
| 61–100 g | 50/1,485 | 1.6 | 1.3–2.1 |
| 101–200 g | 46/1003 | 2.0 | 1.4–2.7 |
| >200 g | 22/395 | 2.1 | 1.3–3.4 |
| Fangchi | |||
| 0 g | 3,927/150,456 | 1.0 | |
| 1–60 g | 623/23,456 | 0.9 | 0.8–1.0 |
| 61–100 g | 15/427 | 0.7 | 0.4–1.2 |
| >100 g | 29/362 | 1.3 | 0.9–2.0 |
| Estimated cumulative dose of aristolochic acid, in mg | |||
| 0 | 3,274/121,820 | 1.0 | |
| 1–150 | 1151/48,869 | 1.0 | 0.96–1.1 |
| 151–250 | 69/2,032 | 1.4 | 1.1–1.8 |
| 251–500 | 64/1,403 | 1.6 | 1.2–2.1 |
| >500 | 36/577 | 2.0 | 1.4–2.9 |
aHazards ratios (HR) and 95% confidence intervals (CI) obtained from Cox proportional hazards regression models with all variables (sex, age, hypertension, diabetes, cumulative dosage of nonsteroidal antiinflammatory drugs, Mu Xiang, Mu-Tong, and Fangchi) fitted simultaneously.
bMultivariable odds ratios were adjusted for potential confounders (sex, age, hypertension, diabetes, chronic hepatitis, chronic urinary tract infection, chronic neuralgia, musculoskeletal disease, cumulative dosage of nonsteroidal antiinflammatory drugs, Mu Xiang, Mu-Tong, and Fangchi) fitted simultaneously.
cMultivariable odds ratios were adjusted for potential confounders (sex, age, hypertension, diabetes, residence in township where black foot disease was endemic, chronic urinary tract infection, Mu Xiang, Mu-Tong, and Fangchi) fitted simultaneously.