Table 5.

Summary of wound closures for selected time points. Values aremean wound area (mm²) ± SEM for untreated wounds and wounds treated with 1% w/w silver sulphadiazine, 7.5% w/w J. flava extract cream (JF), 7.5% w/w L. welwitschii extract cream (LWL), and cream only. N = 5 rats per group. Data analysed by one-way ANOVA followed by Dunnett's multiple comparison test.

Day	Untreated wounds	Silver sulphadiazine (1% w/w)	Cream only	LWL (7.5% w/w)	JF (7.5% w/w)
1	519.62 ± 113.01	460.67 ± 100.78	388.22 ± 119.65	623.80 ± 101.56	453.41 ± 48.99
3	400.59 ± 72.97	290.87 ± 77.59	310.71 ± 111.47	406.40 ± 58.77	374.91 ± 163.66
5	375.50 ± 117.88	194.86 ± 58.56**	242.29 ± 74.09	300.69 ± 55.28	219.87 ± 30.85
7	236.99 ± 45.97	142.43 ± 52.16	159.32 ± 51.24	194.11 ± 71.80	137.92 ± 27.16
9	167.41 ± 42.92	80.47 ± 39.52**	103.44 ± 48.03	134.58 ± 49.26	76.89 ± 23.31**
11	112.74 ± 28.62	24.31 ± 18.70***	57.61 ± 29.41	66.48 ± 21.49*	40.37 ± 18.00**
13	73.00 ± 26.54	13.51 ± 8.70***	33.58 ± 18.89	26.15 ± 12.00**	13.74 ± 8.15***
15	46.14 ± 20.08	2.40 ± 2.93***	19.87 ± 12.15	4.95 ± 3.28**	3.65 ± 2.60***
17	27.72 ± 13.20	0.63 ± 1.40**	9.07 ± 8.29	0.32 ± 0.43**	0.63 ± 0.35**
19	17.67 ± 9.75	0	3.65 ± 4.39**	0	0
21	17.67 ± 9.57	0	0.51 ± 0.78**	0	0

*P < 0.05, **P < 0.01, and ***P < 0.001 were considered statistically significant compared to the untreated wounds.