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. 2013 Oct;98(10):1609–1616. doi: 10.3324/haematol.2013.092700

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Figure 7. — Trilineage differentiation of MSC-derived clones and their allosuppressive potential. (A) Clones generated from CD271-MSC (n=15) and PA-MSCs (n=10) were cultured in induction media for adipocytic, osteoblastic and chondrocytic differentiation. Green bars represent the clones derived from CD271-MSCs, red bars represent the clones derived from PA-MSCs. A: adipocytic; O: osteoblastic; C: chondrocytic; ND: non-differentiated. In addition to trilineage differentiation, six CD271-MSC derived clones (B) and six PA-MSC derived clones (C) were assessed for their allosuppressive potential in mixed lymphocyte reaction (MLR). (D) Representative examples for trilineage differentiation of CD271-MSCs and PA-MSC derived clones (E) into adipocytes, osteoblasts and chondrocytes. Magnification used for microscopic examination of adipocytes was 20x, for osteoblasts 10× and for chondrocytes 40x.