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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: Semin Cancer Biol. 2008 Apr 1;18(5):338–348. doi: 10.1016/j.semcancer.2008.03.018

Figure 2.

Figure 2

Simulation results from all three models for tumors grown under a range of mE background oxygen levels (k) and cell hypoxia tolerance thresholds (h): HDC (upper figure in each square), EHCA (left figure in each square) and IBCell (right figure in each square). Both parameters (k and h) influence the morphology of the tumour: increasing k reduces size and produces fingering, increasing h has a similar, albeit more subtle effect. Colouration for cell types: red (proliferating); green (quiescent); blue (dead).