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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: JAMA Psychiatry. 2013 Mar;70(3):325–333. doi: 10.1001/jamapsychiatry.2013.282

Table 1.

Comparison of select SNPs in cases (N=1459) versus Australian Twin Registry controls (N=1495) and neighborhood controls (N=531) using additive models (additive models - p values are shown)

Gene SNP SNP Location* Minor allele P Value
Heroin-dependent cases vs ATR controls1 Heroin-dependent cases vs neighborhood controls
NCAM1 rs4492854 112488744 G .18 .0073
NCAM1 rs11214546 112611738 A .054 .31
NCAM1 rs587761 112615990 A .55 .0046
NCAM1 rs2186798 112633271 C .045 .056
TTC12 rs2303380 112705919 G .19 .0046
TTC12 rs10891536 112714638 G .027 .010
TTC12 rs4938009 112736138 A .029 .0046
TTC12 rs719804 112739985 G .085 .14
TTC12 rs7130431 112743433 A .12 .00018
TTC12 rs12804573 112746936 G .040 .0014
ANKK1 rs877137 112761540 A .12 .00083
ANKK1 rs877138 112761718 G .037 .00029
ANKK1 rs12360992 112768110 C .25 .0014
ANKK1 rs4938013 112769680 A .069 .00030
ANKK1 rs2734849 112775370 G .30 .0024
ANKK1 rs2734848 112775584 G .016 .0081
ANKK1 rs1800497 112776038 T .93 .12
DRD2 rs2234689 112783693 G .029 .0066
DRD2 rs1554929 112783974 A .34 .0010
DRD2 rs2440390 112792088 A .17 .0091
DRD2 rs1076563 112801119 A .11 .0034
DRD2 rs7125415 112815891 A .011 .22

Abbreviations: ATR, Australian Twin Registry; SNP, single-nucleotide polymorphism

*

From NCBI build 37.2 (National Center for Biotechnology Information).

1

Four principal components (PCs) were included in model for admixture correction.