Table 4.
Comparison of cases (N=1459) with neighborhood controls not dependent on illicit drugs (N=340)
| Group | Risk level indicates number of rs877138 minor alleles plus presence of a rs4492854 major allele | |||
|---|---|---|---|---|
| 0 | 1 | 2 | 3 | |
| Non-dependent neighborhood controls* | 47 (32.4%) | 168 (21.8%) | 107 (15.2%) | 18 (10.1%) |
| Heroin dependent* | 98 (67.6%) | 603 (78.2%) | 598 (84.8%) | 160 (89.9%) |
| Odds-ratio (95% CI) | 1.00 --- |
1.69 (1.15–2.49) | 2.62 (1.75–3.93) | 4.30 (2.36–7.84) |
Mantel-Haenszel chi-square = 35.40 (df =1); p=2.74 × 10−9 (linear trend);
*
Number of individuals are shown with column percentage in parentheses