. 2013 Jul 29;208(9):1464–1473. doi: 10.1093/infdis/jit352

Table 3.

Association Between Cumulative Number of Drugs Below Classification and Regression Tree Analysis–Derived Threshold AUC and Long-term Outcome

Drug AUCs	Long-Term Outcomes		Odds Ratio for Poor Outcome (95% confidence interval)
Drug AUCs	Poor, %	Good, %	Odds Ratio for Poor Outcome (95% confidence interval)
No drug above threshold	1	2	(…)^a
Any 1 drug above threshold	13 (52)	12 (48)	7.57 (2.57–22.34)
Any 2 drugs above threshold	14 (26)	40 (74)	2.65 (0.99–7.18)
All 3 drugs above threshold	7 (12)	53 (88)	Reference
Total	35 (100)	107 (100)

Abbreviation: AUC, 0–24 hour area under the concentration time curve.

^a Combined with “one drug above threshold” due to small cell size.