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RPTPs and neurexins serve as presynaptic hubs by interacting with diverse postsynaptic partners in an isoform- and splice-selective code. Protein families are boxed; interactions lacking physiological relevance indicated as broken lines in Figure 2 in main text are not drawn here; postsynaptic partners at inhibitory synapses are in italics; nonsynaptogenic postsynaptic partners are in gray whereas all others can trigger presynaptic differentiation.
