Figure 1.
These diagrams illustrate similarities between (A) cilia and the (B) immune synapse. IFT20 is associated with the Golgi and vesicles destined for the cilia and is also involved in formation of the immune synapse. Although the entire complement of IFT proteins has not been examined, at least IFT57, IFT88 and the IFT motor Kif3a are also involved in formation of the immune synapse [26]. The centriole, which nucleates the microtubules of the cilium also moves near the cell surface during formation of the immune synapse, positioned between Golgi and the plasma membrane, which sometimes is seen to form a bulge in this area. Figure modified after [53].
