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. Author manuscript; available in PMC: 2013 Oct 3.

Published in final edited form as: Pharm Res. 2010 Dec 4;28(4):776–787. doi: 10.1007/s11095-010-0330-4

Fig. 5 — CPT in micelles reduces cellular content within the CIA joints. Representative joint sections of (A) empty SSM-VIP-injected mice, (B) CPT-SSM-VIP-treated mice; (left to right) CD3+, CD3−, lysozyme+, lysozyme− staining. Bars represent 10 μm. (C) Average pooled immunohistochemical scores of cellular infiltration and distribution in joints of CIA mice on ( ) Day 38 and (▮) Day 60. Results are expressed as mean ± S.E.M. (6 mice/group). *, † p<0.05 versus SSM-VIP and SSM, respectively.

Inline graphic — CPT in micelles reduces cellular content within the CIA joints. Representative joint sections of (A) empty SSM-VIP-injected mice, (B) CPT-SSM-VIP-treated mice; (left to right) CD3+, CD3−, lysozyme+, lysozyme− staining. Bars represent 10 μm. (C) Average pooled immunohistochemical scores of cellular infiltration and distribution in joints of CIA mice on ( ) Day 38 and (▮) Day 60. Results are expressed as mean ± S.E.M. (6 mice/group). *, † p<0.05 versus SSM-VIP and SSM, respectively.