. Author manuscript; available in PMC: 2013 Oct 3.

Published in final edited form as: J Pharm Sci. 2011 Dec 13;101(3):1028–1039. doi: 10.1002/jps.22822

Table 3.

Comparison of m and c Values for Relationships ^mlogD_pr/pl = m^clogP + c in Human and Monkey for Different Sources of ^clogP and Organic Compound Classes

Entry	Species	Source of ^clogP	Compound class	n	r²	m	c
1^a	Human	Cerius2 (version 4.6)	Uncharged	78	0.63	0.449	−0.416
2^a	Human	Cerius2 (version 4.6)	Positively charged	63	0.67	0.463	−1.097
3^b	Human	ACD	Neutral/basic	15	0.430	0.351	−0.834
4^b	Monkey	ACD	Neutral/basic	17	0.574	0.407	−0.268
5^b	Human	Pallas 3.0	Neutral/basic	15	0.385	0.461	−0.067
6^b	Monkey	Pallas 3.0	Neutral/basic	17	0.519	0.504	−0.571

From Ref. 18.

From this study.