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. 2013 Oct 3;8(10):e76533. doi: 10.1371/journal.pone.0076533

Table 5. Predictive values of rifampicin resistance in a hypothetic cohort of 1000 participants.

Index Test 3% Rifampicin Resistance
15% Rifampicin Resistance
30% Rifampicin Resistance
PPV NPV FP FN PPV NPV FP FN PPV NPV FP FN
(95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI)
INNO LiPA 71.0% 99.8% 12 2 93.3% 99.0% 11 9 97.1 97.5% 9 18
(31.1, 85.3) (99.0, 99.9) (72.0, 97.1) (94.6, 99.6) (86.2, 98.8) (87.9, 98.9)
MTBDRplus 59.3% 99.9% 21 1 89.2% 99.3% 18 6 95.3% 98.3% 15 12
(37.7, 69.5) (99.7, 99.9) (77.5, 92.9) (98.3, 99.5) (89.3, 96.9) (95.9, 98.9)
MODS 79.8% 99.9% 8 1 95.8% 99.7% 7 3 98.2% 99.2% 5 6
(35.5, 91.5) (99.6, 99.9) (75.9, 98.4) (97.6, 99.9) (88.4, 99.3) (94.5 99.7)
NRA 93.0% 99.9% 2 1 98.7% 99.6% 2 3 99.5% 99.0% 1 7
(73.0, 96.7) (99.6, 99.9) (93.9, 99.4) (98.0, 99.8) (97.4, 99.8) (95.3, 99.6)
CRI 93.2% 99.9% 2 1 98.7% 99.8% 2 2 99.5% 99.5% 2 4
(74.9, 96.8) (99.8, 99.9) (94.4, 99.4) (99.2, 99.9) (97.6, 99.8) (98.1, 99.8)

CI= Confidence Interval PPV=positive predictive value, NPV=negative predictive value, FP= number of false positive index test results for a cohort of 1000 patients, FN= number of false negative index test results for a cohort of 1000 patient