Table 1. Candidate chromatin insulators.
| Name | Coordinates (hg18) | CTCF scorea | Cell Types w/ CTCFb | Cell Types w/ DHSc |
|---|---|---|---|---|
| Neutral Controls (no CTCF or DHS in K562) | ||||
| XL9 | chr6:3780962-3781708 | 0 | 2 of 23 | 13 of 41 |
| R6 | chr6:124876143-124877183 | 0 | 1 of 23 | 1 of 41 |
| R8 | chr8:84272369-84273367 | 0 | 0 of 23 | 0 of 41 |
| 7C1 | chr7:117168537-117169130 | 0 | 2 of 23 | 2 of 41 |
| CTCF & DHS in Multiple Cell Types | ||||
| 5-1-1 | chr5:131427072-131428071 | 251 | 23 of 23 | 39 of 41 |
| 5-1-2 | chr5:131427572-131428570 | 285 | 23 of 23 | 39 of 41 |
| 5-1-3 | chr5:131428072-131429070 | 285 | 23 of 23 | 40 of 41 |
| 7-1-1 | chr7:117142636-117143715 | 33 | 23 of 23 | 40 of 41 |
| 8-1-1 | chr8:118943357-118944471 | 28 | 22 of 23 | 34 of 41 |
| 11-1-2 | chr11:116166972-116168757 | 65 | 23 of 23 | 39 of 41 |
| Very Strong CTCF in K562 | ||||
| 9-2 | chr9:132923166-132923380 | 1759 | 23 of 23 | 38 of 41 |
| 9-3 | chr9:133043555-133043804 | 1335 | 23 of 23 | 40 of 41 |
| 9-5 | chr9:132911956-132912229 | 1676 | 23 of 23 | 41 of 41 |
| 22-1 | chr22:21850661-21850897 | 1837 | 23 of 23 | 40 of 41 |
| 22-2 | chr22:21231569-21231866 | 2076 | 23 of 23 | 28 of 41 |
| 22-3 | chr22:18524563-18524800 | 1051 | 23 of 23 | 39 of 41 |
(a) CTCF "score" represents the highest ChIP-seq tag density within the designated region in K562 cells.
(b) Number of cell types containing one or more CTCF hot spots in the designated region from a panel of 23 cell types (see Materials and Methods for list).
(c) Number of cell types containing one or more DHS hot spots in the designated region from a panel of 41 cell types (see Materials and Methods for list).