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. 2013 Oct 3;8(10):e76735. doi: 10.1371/journal.pone.0076735

Table 1. Effect of Levetiracetam (LEV, 500 mg/kg i.p.) on lithium-pilocarpine (Li-PIL) -induced seizures in rats.

Groups Median seizure stage (minimum – maximum) Stage 3 seizure latency (min) Stage 3 to 5 seizure incidence (%)
Li-PIL 5 (3-5)* 5.167±0.207a 100*
LEV500 1 (0-3)@ 26.958±2.069b 16.7*,@

In the seizure stage, values are median of 12 rats; statistical comparisons were carried out using Kruskal–Wallis test (nonparametric ANOVA) followed by Dunn’s multiple comparisons test. In the parametric analysis (stage 3-5 seizure latency), values are means of 12 animals ± S.E.M.; statistical comparisons were carried out using one-way ANOVA followed by Student–Newman–Keuls multiple comparisons test. Stage 3-5 seizure incidence (12 animals) was compared using Fisher’s exact probability test as compared to control (*) and Li-PIL (@ groups, P<0.05.