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. 2013 Oct 3;8(10):e76549. doi: 10.1371/journal.pone.0076549

Table 1. Patient characteristics of leptospirosis patients separated according to available data*.

Characteristic Hospitalized and outpatients   Hospitalized patients Hospitalized patients Hospitalized and outpatients
All laboratory confirmed patients Days of acute illness known    Health status after discharge known; Complaints by Passive Case Finding Group Eligible questionnaires; Persistent Complaints by Active Case finding Group
period 1985-2010 1985-2010 1985-2010 1985-1993
n 829 369 236 225
Male 764 (92.3) 332 (90.5) 213 (90.6) 214 (95.5)
Age - median (25th and 75th percentile) 38 (26-52) 38 (25-51) 37 (25-50) 38 (27-51)
Antibiotic treatment ** 653 (86.0) 327 (89.1) 205 (86.9) 171 (83.8)
Hospital admission# 570 (78.9) 368 (100) 236 (100) 129 (73.7)
Deceased no. (%)## 19 (2.3) 0 0 0
Dialysis on hospitalized patients†† 79 (16.1) 46 (12.7) 24 (10.2) 20 (17.9)
ICU admission*** 106 (21.3) 52 (14.5) 31 (13.4) 11 (10.3)
Serogroup known 676 298 192 205
Missing 153 71 44 20
Icterohaemorrhagiae 312 (46.4) 154 (51.7) 92 (47.9) 84 (41.0)
Grippotyphosa 114 (16.9) 57 (19.1) 39 (20.3) 33 (16.1)
Sejroe 110 (16.3) 18 (6.0) 8 (4.2) 67 (32.7)
Pomona 56 (8.3) 28 (9.4) 18 (9.4) 14 (6.8)
Other serogroups 84 (12.4) 41 (13.8) 35 (18.2) 7 (3.4)
Post-leptospirosis complaints
Occurrence CPC NA NA 108 (45.8%) NA
Occurrence PCAC00 NA NA NA 68 (30.2%)
Extreme fatigue NA NA NA 44 (67.7%)
Myalgia NA NA NA 13 (20.0%)
Malaise NA NA NA 11 (16.9%)
Headaches NA NA NA 10 (15.4)
‘Hampered’ physical condition NA NA NA 10 (15.4%)
Joint complaints NA NA NA 6 (9.2%)
Disability to work NA NA NA 9 (13.8%)
Others NA NA NA 27 (41.5%)
Acute injuries
Period 1985-1993 1985-1993 1985-1993 1985-1993
n 332 125 62 225
ARI Yes 165 (61.8) 95 (78.5) 49 (83.1) 111 (59.7)
No 102 (38.2) 26 (21.5) 10 (16.9) 75 (40.3)
Missing 65 4 3 39
Haemorrhage Yes 62 (31.0) 36 (38.7) 19 (38.0) 43 (29.9)
No 138 (69.0) 57 (61.3) 31 (62.0) 101 (70.1)
Missing 132 32 12 81
Liver injury Yes 184 (80.7) 91 (81.3) 46 (80.7) 128 (79.5)
No 44 (19.3) 21 (18.8) 11 (19.3) 33 (20.5)
Missing 104 13 5 64
ALI Yes 27 (19.7) 15 (14.2) 7 (13.7) 15 (16.1)
No 110 (80.3) 91 (85.8) 44 (86.3) 78 (83.9)
Missing 195 19 11  132

NA Is Not Applicable

Values are no. (%) unless otherwise indicated

Sex was registered for 828 patients

**

Data on antibiotic treatment available from respectively 759/829, 367/368, 236/236 and 204/225 patients

Data on hospital admission available from respectively 722/829, 368/368, 236/236 and 175/225 patients

##

18 Patients died in the hospital, 1 patient is unknown

††

Data on dialysis on hospitalized patients available from respectively 491/570, 361/368, 235/236 and 112/129 patients

***

Data on ICU admission on hospitalized patients available from respectively 497/570, 359/368, 231/236 and 107/122 patients

00 Symptoms for PCAC available for 65 cases