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. 2013 Oct 3;8(10):e77334. doi: 10.1371/journal.pone.0077334

Figure 2. DN (CD4-CD8-) T cells have a higher IFNγ functional response than CD4 T cells in blood taken from infants 10 weeks after BCG immunization.

Figure 2

(A) Frequency and (B) median fluorescence intensity (MFI) of IFNγ-expressing CD4 (grey bars) and DN T cells (white bars), and (C) IFNγ total functional response (iMFI) in individuals given BCG at birth (n=28), at 2 months of age (2m; n=26), between 10 and 24 months of age (10-24m; n=7) and in adulthood (n=9). Box plots with lower quartile, median, upper quartile and Tukey whiskers are shown. **: p<0.001, ***: p<0.0001. DN: CD4-CD8- double negative T cells.