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. 2013 Oct 3;8(10):e74578. doi: 10.1371/journal.pone.0074578

Table 5. Topological Characteristics of the protein-protein interaction network of age-correlated genes.

Topological Characteristics in Protein-Protein Interaction Network
Degree Betweenness Centrality Closeness Centrality Clustering Coefficient
Young Middle-aged Old Young Middle-aged Old Young Middle-aged Old Young Middle-aged Old
BA10 13.083 11.894 12.645 6.74E-04 6.14E-04 7.05E-04 0.250 0.249 0.250 0.097 0.103 0.100
Z-score 10.412 8.761 9.009 6.787 5.874 6.968 9.863 8.798 8.827 −1.212 −0.322 −0.750
BA9 10.237 10.774 10.844 5.15E-04 5.45E-04 5.30E-04 0.247 0.247 0.250 0.094 0.101 0.094
Z-score 3.665 7.087 5.806 2.669 5.103 3.720 4.804 8.124 8.546 −1.318 −0.726 −1.595
BA47 11.254 10.516 8.573 6.29E-04 5.29E-04 3.78E-04 0.247 0.246 0.244 0.102 0.102 0.087
Z -score 5.635 6.495 0.940 4.868 4.593 0.453 5.130 7.212 2.705 −0.406 −0.612 −2.074

For each of the three brain regions age-correlated genes divided into three age groups: young (<40 years old), middle-age (between 40 and 59 years old) and old (between 60 and 79 years old).