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. 2013 Oct 3;9(10):e1003682. doi: 10.1371/journal.ppat.1003682

Figure 4. IFNλ regulates PDCD4 in vivo. (A) qRT-PCR analysis of miR-21 in the lungs of WT and IL-28R−/− mice following infection with USA300, µ ± SD.

Figure 4

(B) qRT-PCR analysis of PDCD4 mRNA in the lungs of WT and IL-28R−/− mice following infection with USA300, µ ± SD. (C) Western blot analysis of PDCD4 in the lungs of WT and IL-28R−/− mice following infection with USA300, µ ± SD. (D) Numbers (CFU) of USA300 recovered from BAL of WT and PDCD4−/− mice following 18 hours of infection. (E) Numbers (CFU) of USA300 recovered from lung tissue of WT and PDCD4−/− mice following 18 hours of infection. (F) Trichrome stained lungs from WT and PDCD4−/− mice following and 18 hour USA300 infection (original magnification 100x, insert 400x). (G) ELISA analysis of individual cytokines in BAL of WT and PDCD4−/− mice. Data are representative of at least 2 independent experiments.